Measure the health people can feel

LinkedIn caption
🩺 Measure the health people can feel
Calum MacRae brought a clinical perspective to ARDD 2026: molecular insights need to connect with outcomes that matter in everyday life. In the official recap, he points to a lesson from cardiology. Turning cholesterol and blood pressure from risk markers into useful treatment targets took decades, and lowering a marker did not always improve outcomes. That history matters as geroscience develops new endpoints.
💡 He also emphasized adherence and perceived benefit. A therapy's value depends on whether people experience enough benefit to keep taking it. Sleep, function and intrinsic capacity can help connect biological measurements to that experience. A useful question for the next generation of healthspan trials: what changes will participants actually notice?
#ARDD2026 #Geroscience #ClinicalTrials
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🩺 Calum MacRae at #ARDD2026: aging biomarkers need a clear connection to outcomes people can feel. Sleep, function & intrinsic capacity can help bridge molecular signals and meaningful benefit. A marker needs a clear role and evidence of meaningful clinical benefit.
#Geroscience
Credit: Michael DeStefano
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